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Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells

The transcriptional repressors Hey1 and Hey2 are primary target genes of Notch signaling in the cardiovascular system and induction of Hey gene expression is often interpreted as activation of Notch signaling. Here we report that treatment of primary human endothelial cells with serum or fresh growt...

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Bibliographic Details
Published in: PLOS ONE 10(2015) Artikel-Nummer e0120547, 12 Seiten
Authors and Corporations: Wöltje, Kerstin (Author), Jabs, Markus (Author), Fischer, Andreas (Author)
Other Authors: Jabs, Markus (VerfasserIn) , Fischer, Andreas (VerfasserIn) 1976-
Type of Resource: E-Article
Language: English
March 23, 2015
Series: : PLOS ONE, 10(2015) Artikel-Nummer e0120547, 12 Seiten
Source: Verbunddaten SWB
Lizenzfreie Online-Ressourcen
ISSN: 1932-6203